Product overview:

TRIM56 mouse monoclonal antibody, clone LBI5A1

Field of research:

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Summary:

E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN-beta following detection of pathogen- and host-derived double-stranded DNA. [UniProtKB/Swiss-Prot Function]

Alternative names:

RNF109

Species reactivity:

Human

Host:

Mouse

Target:

TRIM56

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 311-554 of human TRIM56(NP_112223) produced in E.coli.

Clone:

LBI5A1

Conjugation:

Unconjugated

Gene name:

tripartite motif containing 56

Symbol:

TRIM56

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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