Product overview:

SPI1 mouse monoclonal antibody,clone LBI1F3

Field of research:

Acute myeloid leukemia, Pathways in cancer

Summary:

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

OF; PU.1; SFPI1; SPI-1; SPI-A

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

SPI1

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human SPI1(NP_003111) produced in E.coli.

Clone:

LBI1F3

Conjugation:

Unconjugated

Gene name:

Spi-1 proto-oncogene

Symbol:

SPI1

Pathway:

Acute myeloid leukemia, Pathways in cancer

Function:

Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com