Product overview:

MAK mouse monoclonal antibody, clone LBI4H4

Field of research:

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Summary:

The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Alternative names:

dJ417M14.2; RP62

Species reactivity:

Human, Rat

Host:

Mouse

Target:

MAK

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 291-623 of human MAK(NP_005897) produced in E.coli.

Clone:

LBI4H4

Conjugation:

Unconjugated

Gene name:

male germ cell associated kinase

Symbol:

MAK

Pathway:

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Function:

Druggable Genome, Protein Kinase

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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