Product overview:

ICOSLG mouse monoclonal antibody, clone LBI2C5

Field of research:

Cell adhesion molecules (CAMs)

Summary:

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. [UniProtKB/Swiss-Prot Function]

Alternative names:

B7-H2; B7h; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS

Species reactivity:

Human

Host:

Mouse

Target:

ICOSLG

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human ICOSLG (NP_056074) produced in HEK293T cell.

Clone:

LBI2C5

Conjugation:

Unconjugated

Gene name:

inducible T-cell costimulator ligand

Symbol:

ICOSLG

Pathway:

Cell adhesion molecules (CAMs)

Function:

Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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