Product overview:

CNOT2 mouse monoclonal antibody, clone LBI5A12

Field of research:

RNA degradation

Summary:

This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

Alternative names:

CDC36; HSPC131; NOT2; NOT2H

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

CNOT2

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human CNOT2(NP_055330) produced in E.coli.

Clone:

LBI5A12

Conjugation:

Unconjugated

Gene name:

CCR4-NOT transcription complex subunit 2

Symbol:

CNOT2

Pathway:

RNA degradation

Function:

Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com