Product overview:

AAAS mouse monoclonal antibody, clone LBI5B10

Field of research:

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Summary:

The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Alternative names:

AAA; AAASb; ADRACALA; ADRACALIN; ALADIN; GL003

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

AAAS

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 322-546 of human AAAS(NP_056480) produced in E.coli.

Clone:

LBI5B10

Conjugation:

Unconjugated

Gene name:

aladin WD repeat nucleoporin

Symbol:

AAAS

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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