Product overview:

EGLN2 mouse monoclonal antibody, clone LBI7H3

Field of research:

Pathways in cancer, Renal cell carcinoma

Summary:

The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011]

Alternative names:

EIT6; HIF-PH1; HIFPH1; HPH-1; HPH-3; PHD1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

EGLN2

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human EGLN2(NP_542770) produced in E.coli.

Clone:

LBI7H3

Conjugation:

Unconjugated

Gene name:

egl-9 family hypoxia inducible factor 2

Symbol:

EGLN2

Pathway:

Pathways in cancer, Renal cell carcinoma

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com