Product overview:

AMTN mouse monoclonal antibody, clone LBI1D6

Field of research:

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Summary:

The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]). [supplied by OMIM, Mar 2008]. Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is 1 aa shorter compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC121812.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

Alternative names:

UNQ689

Species reactivity:

Human

Host:

Mouse

Target:

AMTN

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human AMTN (NP_997722) produced in E.coli.

Clone:

LBI1D6

Conjugation:

Unconjugated

Gene name:

amelotin

Symbol:

AMTN

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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