Product overview:

IRS1 mouse monoclonal antibody, clone LBI9E11

Field of research:

Adipocytokine signaling pathway, Insulin signaling pathway, Neurotrophin signaling pathway, Type II diabetes mellitus

Summary:

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]

Alternative names:

HIRS-1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

IRS1

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-280 of human IRS1(NP_005535) produced in E.coli.

Clone:

LBI9E11

Conjugation:

Unconjugated

Gene name:

insulin receptor substrate 1

Symbol:

IRS1

Pathway:

Adipocytokine signaling pathway, Insulin signaling pathway, Neurotrophin signaling pathway, Type II diabetes mellitus

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com