Product overview:

CHMP5 mouse monoclonal antibody, clone LBI5C7

Field of research:

Endocytosis

Summary:

CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]). [supplied by OMIM, Mar

Alternative names:

C9orf83; CGI-34; HSPC177; PNAS-2; SNF7DC2; Vps60

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

CHMP5

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human CHMP5 (NP_057494) produced in E.coli.

Clone:

LBI5C7

Conjugation:

Unconjugated

Gene name:

charged multivesicular body protein 5

Symbol:

CHMP5

Pathway:

Endocytosis

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com