Product overview:

TARBP2 mouse monoclonal antibody, clone LBI7C1

Field of research:

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Summary:

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008]

Alternative names:

LOQS; TRBP; TRBP1; TRBP2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

TARBP2

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human TARBP2 (NP_004169) produced in E.coli.

Clone:

LBI7C1

Conjugation:

Unconjugated

Gene name:

TARBP2, RISC loading complex RNA binding subunit

Symbol:

TARBP2

Pathway:

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Function:

Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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