Product overview:

HIST1H2BA mouse monoclonal antibody, clone LBI1C9

Field of research:

Systemic lupus erythematosus

Summary:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Jul 2008]

Alternative names:

bA317E16.3; H2BFU; STBP; TH2B; TSH2B; TSH2B.1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

H2BC1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 2-127 of human HIST1H2BA(NP_733759) produced in E.coli.

Clone:

LBI1C9

Conjugation:

Unconjugated

Gene name:

histone cluster 1, H2ba

Symbol:

H2BC1

Pathway:

Systemic lupus erythematosus

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com