Product overview:

TCAP mouse monoclonal antibody, clone LBI5E12

Field of research:

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Summary:

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008]

Alternative names:

CMD1N; CMH25; LGMD2G; T-cap; TELE; telethonin

Species reactivity:

Human, Mouse

Host:

Mouse

Target:

TCAP

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human TCAP (NP_003664) produced in E.coli.

Clone:

LBI5E12

Conjugation:

Unconjugated

Gene name:

titin-cap

Symbol:

TCAP

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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