Product overview:

MAVS mouse monoclonal antibody, clone LBI9C4

Field of research:

Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway

Summary:

This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Alternative names:

CARDIF; IPS-1; IPS1; VISA

Species reactivity:

Human

Host:

Mouse

Target:

MAVS

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-247 of human MAVS(NP_065797) produced in E.coli.

Clone:

LBI9C4

Conjugation:

Unconjugated

Gene name:

mitochondrial antiviral signaling protein

Symbol:

MAVS

Pathway:

Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway

Function:

Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com