Product overview:

FERMT3 mouse monoclonal antibody,clone LBI2H10

Field of research:

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Summary:

Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010]

Alternative names:

KIND3; MIG-2; MIG2B; UNC112C; URP2; URP2SF

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

FERMT3

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 259-528 of human FERMT3(NP_113659) produced in E.coli.

Clone:

LBI2H10

Conjugation:

Unconjugated

Gene name:

fermitin family member 3

Symbol:

FERMT3

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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