Product overview:

CTBP2 mouse monoclonal antibody, clone LBI4D4

Field of research:

Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway

Summary:

This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]

Alternative names:

C-terminal binding protein 2; OTTHUMP00000020699; OTTHUMP00000020701; ribeye

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

CTBP2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 233-336 of human CTBP2(NP_073713) produced in E.coli.

Clone:

LBI4D4

Conjugation:

Unconjugated

Gene name:

C-terminal binding protein 2

Symbol:

CTBP2

Pathway:

Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway

Function:

Stem cell - Pluripotency, Stem cell relevant signaling - Wnt Signaling pathway

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com