Product overview:

GPNMB mouse monoclonal antibody,clone LBI2E10

Field of research:

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Summary:

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

HGFIN; NMB

Species reactivity:

Human

Host:

Mouse

Target:

GPNMB

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human GPNMB (NP_001005340) produced in HEK293T cell.

Clone:

LBI2E10

Conjugation:

Unconjugated

Gene name:

glycoprotein nmb

Symbol:

GPNMB

Pathway:

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Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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