Product overview:

APPL1 mouse monoclonal antibody,clone LBI4B11

Field of research:

Colorectal cancer, Pathways in cancer

Summary:

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]

Alternative names:

APPL; DIP13alpha; MODY14

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

APPL1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human APPL1 (NP_036228) produced in HEK293T cell.

Clone:

LBI4B11

Conjugation:

Unconjugated

Gene name:

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

Symbol:

APPL1

Pathway:

Colorectal cancer, Pathways in cancer

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com