Product overview:

BAMBI mouse monoclonal antibody,clone LBI9G4

Field of research:

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Summary:

This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]

Alternative names:

NMA

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

BAMBI

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 21-152 of human BAMBI(NP_036474) produced in E.coli.

Clone:

LBI9G4

Conjugation:

Unconjugated

Gene name:

BMP and activin membrane-bound inhibitor

Symbol:

BAMBI

Pathway:

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Function:

Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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