Product overview:

DMRT1 mouse monoclonal antibody, clone LBI2H1

Field of research:

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Summary:

This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]

Alternative names:

CT154; DMT1

Species reactivity:

Human

Host:

Mouse

Target:

DMRT1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-210 of human DMRT1(NP_068770) produced in E.coli.

Clone:

LBI2H1

Conjugation:

Unconjugated

Gene name:

doublesex and mab-3 related transcription factor 1

Symbol:

DMRT1

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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