Product overview:

CPB2 mouse monoclonal antibody, clone LBI3D5

Field of research:

Complement and coagulation cascades

Summary:

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun

Alternative names:

CPU; PCPB; TAFI

Species reactivity:

Human

Host:

Mouse

Target:

CPB2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 224-423 of human CPB2(NP_001863) produced in E.coli.

Clone:

LBI3D5

Conjugation:

Unconjugated

Gene name:

carboxypeptidase B2

Symbol:

CPB2

Pathway:

Complement and coagulation cascades

Function:

Druggable Genome, Protease, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com