Product overview:

IGFBP3 mouse monoclonal antibody, clone LBI8E11

Field of research:

p53 signaling pathway

Summary:

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Alternative names:

BP-53; IBP3

Species reactivity:

Human

Host:

Mouse

Target:

IGFBP3

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 28-297 of human IGFBP3(NP_001013416) produced in E.coli.

Clone:

LBI8E11

Conjugation:

Unconjugated

Gene name:

insulin like growth factor binding protein 3

Symbol:

IGFBP3

Pathway:

p53 signaling pathway

Function:

Druggable Genome, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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