Product overview:

PON3 mouse monoclonal antibody, clone LBI5C3

Field of research:

Metabolic pathways

Summary:

This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized. [provided by RefSeq, Jul 2008]

Alternative names:

lactonase 3; paraoxanase-3; paraoxonase 3; serum paraoxonase

Species reactivity:

Human

Host:

Mouse

Target:

PON3

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 30-319 of human PON3(NP_000931) produced in E.coli.

Clone:

LBI5C3

Conjugation:

Unconjugated

Gene name:

paraoxonase 3

Symbol:

PON3

Pathway:

Metabolic pathways

Function:

Secreted Protein, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com