Product overview:

FBLIM1 mouse monoclonal antibody, clone LBI3F8

Field of research:

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Summary:

This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul

Alternative names:

CAL; FBLP-1; FBLP1

Species reactivity:

Human

Host:

Mouse

Target:

FBLIM1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-242 of (NP_060026) produced in E.coli.

Clone:

LBI3F8

Conjugation:

Unconjugated

Gene name:

filamin binding LIM protein 1

Symbol:

FBLIM1

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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