Product overview:

ANGPT1 mouse monoclonal antibody, clone LBI8C5

Field of research:

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Summary:

Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2010]

Alternative names:

AGP1; AGPT; ANG1; HAE5

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ANGPT1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 20-320 of human ANGPT1(NP_001137) produced in E.coli.

Clone:

LBI8C5

Conjugation:

Unconjugated

Gene name:

angiopoietin 1

Symbol:

ANGPT1

Pathway:

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Function:

Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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