Product overview:

OXT mouse monoclonal antibody, clone LBI5G4

Field of research:

Request info at info@sobekbio.com

Summary:

This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013]

Alternative names:

OT; OT-NPI; OXT-NPI

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

OXT

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 20-125 of human OXT(NP_000906) produced in E.coli.

Clone:

LBI5G4

Conjugation:

Unconjugated

Gene name:

oxytocin/neurophysin I prepropeptide

Symbol:

OXT

Pathway:

Request info at info@sobekbio.com

Function:

Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com