Product overview:

ROR1 mouse monoclonal antibody, clone LBI3D11

Field of research:

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Summary:

This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun

Alternative names:

dJ537F10.1; NTRKR1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ROR1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human ROR1 (NP_005003) produced in HEK293T cell.

Clone:

LBI3D11

Conjugation:

Unconjugated

Gene name:

receptor tyrosine kinase-like orphan receptor 1

Symbol:

ROR1

Pathway:

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Function:

Druggable Genome, Protein Kinase, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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