Product overview:

JAK2 mouse monoclonal antibody, clone LBI7D12

Field of research:

Adipocytokine signaling pathway, Chemokine signaling pathway, Jak-STAT signaling pathway

Summary:

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008]

Alternative names:

JTK10; THCYT3

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

JAK2

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 297-596 of human JAK2(NP_004963) produced in E.coli.

Clone:

LBI7D12

Conjugation:

Unconjugated

Gene name:

Janus kinase 2

Symbol:

JAK2

Pathway:

Adipocytokine signaling pathway, Chemokine signaling pathway, Jak-STAT signaling pathway

Function:

Druggable Genome, Protein Kinase

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com