Product overview:

PROZ mouse monoclonal antibody, clone LBI3E5

Field of research:

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Summary:

This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Alternative names:

PZ

Species reactivity:

Human

Host:

Mouse

Target:

PROZ

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 115-400 of human PROZ(NP_003882) produced in E.coli.

Clone:

LBI3E5

Conjugation:

Unconjugated

Gene name:

protein Z, vitamin K dependent plasma glycoprotein

Symbol:

PROZ

Pathway:

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Function:

Druggable Genome, Protease, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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