Product overview:

GABRA5 mouse monoclonal antibody, clone LBI3H7

Field of research:

Neuroactive ligand-receptor interaction

Summary:

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]

Alternative names:

MGC138184

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

GABRA5

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 32-259 of human GABRA5(NP_000801) produced in E.coli.

Clone:

LBI3H7

Conjugation:

Unconjugated

Gene name:

gamma-aminobutyric acid type A receptor alpha5 subunit

Symbol:

GABRA5

Pathway:

Neuroactive ligand-receptor interaction

Function:

Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com