Product overview:

BCL2 mouse monoclonal antibody, clone LBI5H8

Field of research:

Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Focal adhesion, Neurotrophin signaling pathway, Pathways in cancer, Prostate cancer, Small cell lung cancer

Summary:

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008]

Alternative names:

Bcl-2; PPP1R50

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

BCL2

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human BCL2 (NP_000624) produced in HEK293T cell.

Clone:

LBI5H8

Conjugation:

Unconjugated

Gene name:

B-cell CLL/lymphoma 2

Symbol:

BCL2

Pathway:

Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Focal adhesion, Neurotrophin signaling pathway, Pathways in cancer, Prostate cancer, Small cell lung cancer

Function:

Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com