Product overview:

NCOA4 mouse monoclonal antibody, clone LBI2G10

Field of research:

Pathways in cancer, Thyroid cancer

Summary:

This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14. [provided by RefSeq, Feb 2009]

Alternative names:

ARA70; ELE1; PTC3; RFG

Species reactivity:

Human

Host:

Mouse

Target:

NCOA4

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 280-553 of human NCOA4(NP_001138732) produced in E.coli.

Clone:

LBI2G10

Conjugation:

Unconjugated

Gene name:

nuclear receptor coactivator 4

Symbol:

NCOA4

Pathway:

Pathways in cancer, Thyroid cancer

Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com