Product overview:

RARA mouse monoclonal antibody, clone LBI2D5

Field of research:

Acute myeloid leukemia, Pathways in cancer

Summary:

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus. [provided by RefSeq, Sep 2010]

Alternative names:

NR1B1; RAR

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

RARA

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 52-299 of human RARA(NP_000955) produced in E.coli.

Clone:

LBI2D5

Conjugation:

Unconjugated

Gene name:

retinoic acid receptor alpha

Symbol:

RARA

Pathway:

Acute myeloid leukemia, Pathways in cancer

Function:

Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com