Product overview:

SPP1 mouse monoclonal antibody, clone LBI6C12

Field of research:

ECM-receptor interaction, Focal adhesion, Toll-like receptor signaling pathway

Summary:

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Alternative names:

BNSP; BSPI; ETA-1; OPN

Species reactivity:

Human

Host:

Mouse

Target:

SPP1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 17-314 of human SPP1(NP_001035147) produced in E.coli.

Clone:

LBI6C12

Conjugation:

Unconjugated

Gene name:

secreted phosphoprotein 1

Symbol:

SPP1

Pathway:

ECM-receptor interaction, Focal adhesion, Toll-like receptor signaling pathway

Function:

Druggable Genome, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com