Product overview:

GRK4 mouse monoclonal antibody, clone LBI4F5

Field of research:

Chemokine signaling pathway, Endocytosis

Summary:

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Alternative names:

GPRK2L; GPRK4; GRK4a; IT11

Species reactivity:

Human

Host:

Mouse

Target:

GRK4

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-245 of human GRK4(NP_892027) produced in E.coli.

Clone:

LBI4F5

Conjugation:

Unconjugated

Gene name:

G protein-coupled receptor kinase 4

Symbol:

GRK4

Pathway:

Chemokine signaling pathway, Endocytosis

Function:

Druggable Genome, Protein Kinase

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com