Product overview:

PTGS2 mouse monoclonal antibody, clone LBI10H5

Field of research:

Arachidonic acid metabolism, Pathways in cancer, Small cell lung cancer, VEGF signaling pathway

Summary:

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]

Alternative names:

COX-2; COX2; GRIPGHS; hCox-2; PGG/HS; PGHS-2; PHS-2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PTGS2

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 18-260 of human PTGS2 (NP_000954) produced in E.coli.

Clone:

LBI10H5

Conjugation:

Unconjugated

Gene name:

prostaglandin-endoperoxide synthase 2

Symbol:

PTGS2

Pathway:

Arachidonic acid metabolism, Pathways in cancer, Small cell lung cancer, VEGF signaling pathway

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com