Product overview:

CAPN5 mouse monoclonal antibody, clone LBI4E11

Field of research:

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Summary:

Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3. [provided by RefSeq, Jul 2008]

Alternative names:

ADNIV; HTRA3; nCL-3; VRNI

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

CAPN5

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 274-578 of human CAPN5 (NP_004046) produced in E.coli.

Clone:

LBI4E11

Conjugation:

Unconjugated

Gene name:

calpain 5

Symbol:

CAPN5

Pathway:

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Function:

Druggable Genome, Protease

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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