Product overview:

PPP1R8 mouse monoclonal antibody, clone LBI5H9

Field of research:

Request info at info@sobekbio.com

Summary:

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul

Alternative names:

ARD-1; ARD1; NIPP-1; NIPP1; PRO2047

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PPP1R8

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-225 of human PPP1R8 (NP_612568) produced in E.coli.

Clone:

LBI5H9

Conjugation:

Unconjugated

Gene name:

protein phosphatase 1 regulatory subunit 8

Symbol:

PPP1R8

Pathway:

Request info at info@sobekbio.com

Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com