Product overview:

Purified PAFAH1B3 mouse monoclonal antibody, clone LBI2A5

Field of research:

Ether lipid metabolism, Metabolic pathways

Summary:

This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

Alternative names:

PAFAHG

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PAFAH1B3

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human PAFAH1B3 (NP_001139411) produced in E.coli.

Clone:

LBI2A5

Conjugation:

Unconjugated

Gene name:

platelet activating factor acetylhydrolase 1b catalytic subunit 3

Symbol:

PAFAH1B3

Pathway:

Ether lipid metabolism, Metabolic pathways

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com