Product overview:

BFSP2 mouse monoclonal antibody, clone LBI4E7

Field of research:

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Summary:

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex. [provided by RefSeq, Jun 2009]

Alternative names:

CP47; CP49; CTRCT12; LIFL-L; PHAKOSIN

Species reactivity:

Human, Rat

Host:

Mouse

Target:

BFSP2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 184-415 of human BFSP2 (NP_003562) produced in E.coli.

Clone:

LBI4E7

Conjugation:

Unconjugated

Gene name:

beaded filament structural protein 2

Symbol:

BFSP2

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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