Product overview:

Purified CCL19 mouse monoclonal antibody, clone LBI6A3

Field of research:

Chemokine signaling pathway, Cytokine-cytokine receptor interaction

Summary:

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Jul 2008]

Alternative names:

CKb11; ELC; MIP-3b; MIP3B; SCYA19

Species reactivity:

Human

Host:

Mouse

Target:

CCL19

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 22-98 of human CCL19 (NP_006265) produced in E.coli.

Clone:

LBI6A3

Conjugation:

Unconjugated

Gene name:

C-C motif chemokine ligand 19

Symbol:

CCL19

Pathway:

Chemokine signaling pathway, Cytokine-cytokine receptor interaction

Function:

Druggable Genome, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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