Product overview:

Purified FOSB mouse monoclonal antibody, clone LBI2G5

Field of research:

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Summary:

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

AP-1; G0S3; GOS3; GOSB

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

FOSB

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-255 of human FOSB (NP_006723) produced in E.coli.

Clone:

LBI2G5

Conjugation:

Unconjugated

Gene name:

FosB proto-oncogene, AP-1 transcription factor subunit

Symbol:

FOSB

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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