Product overview:

GNG7 mouse monoclonal antibody, clone LBI3G1

Field of research:

Chemokine signaling pathway

Summary:

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum. [UniProtKB/Swiss-Prot Function]

Alternative names:

FLJ00058

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

GNG7

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 2-65 of human GNG7(NP_443079) produced in E.coli.

Clone:

LBI3G1

Conjugation:

Unconjugated

Gene name:

G protein subunit gamma 7

Symbol:

GNG7

Pathway:

Chemokine signaling pathway

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com