Product overview:

NAB2 mouse monoclonal antibody, clone LBI1B10

Field of research:

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Summary:

This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Alternative names:

MADER

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

NAB2

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 178-442 of human NAB2 (NP_005958) produced in E.coli.

Clone:

LBI1B10

Conjugation:

Unconjugated

Gene name:

NGFI-A binding protein 2

Symbol:

NAB2

Pathway:

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Function:

Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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