Product overview:

LMNB2 mouse monoclonal antibody, clone LBI2C6

Field of research:

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Summary:

This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy. [provided by RefSeq, May 2012]

Alternative names:

EPM9; LAMB2; LMN2; MCPH27

Species reactivity:

Human

Host:

Mouse

Target:

LMNB2

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human LMNB2 (NP_116126) produced in HEK293T cell.

Clone:

LBI2C6

Conjugation:

Unconjugated

Gene name:

lamin B2

Symbol:

LMNB2

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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