Product overview:

UBE2B mouse monoclonal antibody, clone LBI1E11

Field of research:

Ubiquitin mediated proteolysis

Summary:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq, Jul 2008]

Alternative names:

E2-17kDa; HHR6B; HR6B; RAD6B; UBC2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

UBE2B

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human UBE2B (NP_003328) produced in E.coli.

Clone:

LBI1E11

Conjugation:

Unconjugated

Gene name:

ubiquitin conjugating enzyme E2 B

Symbol:

UBE2B

Pathway:

Ubiquitin mediated proteolysis

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com