Product overview:

VWF mouse monoclonal antibody, clone LBI9B3

Field of research:

Complement and coagulation cascades, ECM-receptor interaction, Focal adhesion

Summary:

The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]

Alternative names:

F8VWF; VWD

Species reactivity:

Human

Host:

Mouse

Target:

VWF

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 764-1263 of human VWF (NP_000543) produced in SF9 cell.

Clone:

LBI9B3

Conjugation:

Unconjugated

Gene name:

von Willebrand factor

Symbol:

VWF

Pathway:

Complement and coagulation cascades, ECM-receptor interaction, Focal adhesion

Function:

Druggable Genome, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com