Product overview:

ISCU mouse monoclonal antibody, clone LBI8H2

Field of research:

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Summary:

Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. [provided by RefSeq, Jul 2008]

Alternative names:

2310020H20Rik; HML; hnifU; ISU2; NIFU; NIFUN

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ISCU

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human ISCU (NP_055116) produced in E.coli.

Clone:

LBI8H2

Conjugation:

Unconjugated

Gene name:

iron-sulfur cluster assembly enzyme

Symbol:

ISCU

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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