Product overview:

ITGB3BP mouse monoclonal antibody, clone LBI4H1

Field of research:

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Summary:

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

Alternative names:

CENP-R; CENPR; HSU37139; NRIF3; TAP20

Species reactivity:

Human

Host:

Mouse

Target:

ITGB3BP

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human ITGB3BP (NP_055103) produced in E.coli.

Clone:

LBI4H1

Conjugation:

Unconjugated

Gene name:

integrin subunit beta 3 binding protein

Symbol:

ITGB3BP

Pathway:

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Function:

Druggable Genome, Stem cell - Pluripotency, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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