Product overview:

NR2C1 mouse monoclonal antibody, clone LBI1E9

Field of research:

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Summary:

This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

Alternative names:

TR2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

NR2C1

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-237 of human NR2C1 (NP_001027458) produced in E.coli.

Clone:

LBI1E9

Conjugation:

Unconjugated

Gene name:

nuclear receptor subfamily 2 group C member 1

Symbol:

NR2C1

Pathway:

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Function:

Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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